P2408 - Scientist/Senior Scientist Oncology, Translational Pharmacology
Debiopharm
- Lausanne
- CDI
- Temps-plein
- Design, plan, manage and report primary and secondary pharmacology studies performed in Contract Research Organizations:
- In vitro/in vivo pharmacology compounds selection and profiling, including off-target characterization
- Proof of concept in vivo studies – PK/PD
- Mechanism of action studies
- Propose innovative solutions to develop new compounds
- Identify the intellectual property, inventions and innovation opportunities, and collaborate with legal department to feed DPI’s patent portfolio
- Identify and develop the clinical pharmacodynamic biomarkers assays to be implemented in clinical studies.
- Participate in the preparation of the pharmacology documentation for health authorities (e.g investigator drug brochures, informed consent forms, lab manuals, clinical protocols and reports)
- Participate in internal and external scientific communications
- Participate in due diligence and contribute to in/out licensing activities
PhD in the field of biomedical research, biomedical engineering or equivalent
- At least 5-year experience in antibody discovery & development in oncology in pharma or biotech
- Experience with in silico and/or in vitro and/or in vivo experimental approaches to characterize antibody mode of action
- Experience in antibody-drug conjugated and/or bi-specific antibody development
- Knowledge of animal welfare regulations
- Experience in bioinformatics is a plus
- Experience in selection and management of Contract Research Organizations
- Excellent communication skills (oral and written) in English
- You are solution-oriented, resilient to push forward the R&D projects and look to work on complex and innovative compounds, willing to be hands-on in activities
- You have excellent commend of data analysis and visualization tools and have good IT skills
- You are used in working in cross-functional team and fast-paced environment and are a team player, looking to tackle challenges together with your team
- You are curious and you propose innovative solutions
- International, highly dynamic environment with a long-term vision.
- Cross-functional collaboration at the forefront of the most advanced scientific developments in oncology and anti-bacterial industry
- Exposure to a wide variety of areas and functions within clinical development and the pharmaceutical industry
- Participation in a company where innovation, people and entrepreneurship are the fundamental keys to success.
- Proud to be an Equal-Pay certified, we ensure offering to all our employees the same opportunities